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Friday, March 29, 2013
The Ocean Is Safe from Swarms of Man-Sized Robo-Jellyfish?For Now
Taylor Swift Has Fans Sobbing, Squealing, Soaring On Red Tour
Swift takes fans on emotional rollercoaster and 'rewards' them with Neon Trees' Tyler Glenn.
By Emilee Lindner
Taylor Swift performs in Newark, New Jersey Thursday night
Photo: WireImage
Source: http://www.mtv.com/news/articles/1704572/taylor-swift-red-tour-new-jersey.jhtml
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Wall St edges higher as S&P 500 tops record close
By Chuck Mikolajczak
NEW YORK (Reuters) - U.S. stocks edged higher on Thursday, with the S&P 500 rising just above its record closing high, which has acted as a significant resistance point in recent weeks.
The S&P had been caught in a range, having traded within 10 points of the record closing high of 1,565.15 over the prior 13 sessions before successfully piercing that level on Thursday, while buyers moved in on signs of weakness to quickly eliminate any declines.
A close above the record level could signify more gains, although investors may tread lightly with government payroll data and corporate earnings season on the horizon.
"A close at a high is good for investor confidence. It may attract a little bit of near term activity," said Fred Dickson, chief market strategist at D.A. Davidson & Co in Lake Oswego, Oregon.
"We are still trying to climb a grudging wall of worry regarding economic momentum and that means we are not going to sprint ahead as we take off into April."
The Dow Jones industrial average gained 43.12 points, or 0.30 percent, to 14,569.28. The Standard & Poor's 500 Index gained 3.60 points, or 0.23 percent, to 1,566.45. The Nasdaq Composite Index gained 3.64 points, or 0.11 percent, to 3,260.16.
U.S. stocks were set to close out a strong quarter with the S&P 500 up 9.8 percent for the first three months of 2013. The Dow was up 11.2 percent and the Nasdaq up 8 percent. For the month, the S&P is up 3.4 percent, the Dow is up 3.7 percent and the Nasdaq is up 3.1 percent.
Thursday is the U.S. stock markets' last trading day of the quarter due to the Good Friday holiday.
Data showed the number of Americans filing new claims for unemployment benefits rose more than expected last week, but probably not enough to suggest a faltering in the labor market recovery. Other data showed the economy expanded more in the fourth quarter than was prevously estimated by the government.
The Institute for Supply Management-Chicago business barometer showed the pace of business activity in the Midwest slowed in March as the new order rate tumbled.
In a positive sign, Cypriots lined up as banks reopened despite tight controls imposed on transactions. There was no sign of a run on deposits, as feared, after the government was forced to accept a stringent EU rescue package.
BlackBerry
Chesapeake Energy Corp's
Influential proxy advisory firm ISS threw its weight behind opponents of MetroPCS Communications Inc's
JPMorgan Chase & Co
(Additional reporting by Ryan Vlastelica; Editing by Kenneth Barry)
Source: http://news.yahoo.com/wall-st-edges-higher-p-500-tops-record-160839732--finance.html
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Ride Out North Korea's Preemptive Strike in These 24 Cold War Fallout Shelters
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If Steve King Runs for the Senate, His Opponents Will Have a Lot to Work With
Earlier this month Rep. Steve King said there was a better than 50 percent chance he would run for the Senate seat being vacated by Sen. Tom Harkin of Iowa. A staunch conservative with a history of saying inflammatory things, is a divisive political figure by any calculation. To take the state, he?d have to overcome money from a Karl Rove organization aimed at preventing fringe GOP candidates from winning primaries, and win over districts far less conservative than his own. But his biggest obstacle may be overcoming 10-plus years of giving his opponents sound bites to use against him. Here are a few that you?ll likely hear on repeat if he runs.
Compared Immigrants to Dogs.?During last year?s campaign, King made news when his comment at a town hall seemed to paint a parallel between immigrants and canines. In talking about which immigrants should be allowed to come into this country, King drew from his hunting experience for a metaphor: ?You want a good bird dog?? he told the crowd in Pocahontas, Iowa. ?You want one that?s going to be aggressive? Pick the one that?s the friskiest ? not the one that?s over there sleeping in the corner.? King went on to say that the United States should have ?the pick of the litter.?
Later, King would tell reporters that he meant no harm by the comment and that it was being blown out of proportion.
"It was a compliment.... They knew it was a compliment; they turned it into an insult because they're professional hyperventilators,? he said.
Waded into Legitimate Rape Debate.?Former Rep. Todd Akin of Missouri is the poster child for why Karl Rove feels the need to fight fringe GOP candidates. His comment about ?legitimate rape? became all anyone could talk about during the last election, and very well could have kept Missouri in Democratic hands.
And King just couldn?t stop himself from becoming part of the conversation. As a cosponsor of a bill called the ?No Taxpayers Funding for Abortion Act,? King was asked whether exemptions should be made for victims of statutory rape or incest, such as a 12-year-old girl who gets pregnant.
"Well I just haven't heard of that being a circumstance that's been brought to me in any personal way,? he said. ?I'd be open to discussion about that subject matter.?
Various media outlets picked up this comment as a sign that King may have partially agreed with Akin?s stance. And while his statement wasn't nearly as controversial as Akin?s comments at the time, it is likely to become part of the conversation in a senatorial election.
Called Joe McCarthy a Hero.?Sen. Joseph McCarthy?s name has become synonymous with witch hunts. And yet, in 2005, King called the former chairman of the House Committee on Un-American Activities, or HUAC, a ?hero.?
?His tactics were relentless, his personality invidious, and his habits sometimes excessive,? King said. ?Nonetheless, he was a central figure in the movement to remove communist spies and sympathizers from our most sensitive government positions.?
And that was not just a one-time declaration. For years, King has been pushing the sentiment, saying?in 2010 that he supported the reestablishment of HUAC, ?"but I would support a different committee name so that we don't have to deal with the history, and move forward."
Is Not a Fan of Gay Marriage.?When the Iowa Supreme Court ruled that same-sex couples could marry in the state, King warned that the Hawkeye State could become the ?mecca? for gay marriage.? Anyone who didn?t already know how he felt about the issue needn?t look any further than a 2003 press release King issued after a Sioux City judge granted a divorce to a lesbian couple.
?Unicorns, leprechauns, gay marriages in Iowa ? these are all things you will never find, because they just don?t exist,? he said.
But, if you want to look beyond that view, check out King?claimiing that?same-sex marriage is really just a push for socialism.
Says He Might Start His Own Country, Anyway.?Democrats don't want King to become senator, and Rove and other Republicans worry he may hurt their chances at picking up the seat. They might prefer that he start his own country somewhere and stay out of Iowa. Who knows, maybe he will. After the House passed the Affordable Care Act in 2010, King told a crowd of tea-party activists he was thinking about it.?
"If I could start a country with a bunch of people, they?d be the folks who were standing with us the last few days," he told the crowd. "Let?s hope we don?t have to do that!?Let?s beat that other side to a pulp! Let?s take them out. Let?s chase them down. There?s going to be a reckoning!"
Source: http://news.yahoo.com/steve-king-runs-senate-opponents-lot-135044973--politics.html
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Historic expulsion vote pending in Nevada Assembly
CARSON CITY, Nev. (AP) ? Members of the Nevada Assembly are poised for a historic vote on whether to oust one of their own ? something only contemplated once in the early years of Nevada's statehood but never carried out.
A vote on whether to expel troubled Assemblyman Steven Brooks was anticipated Wednesday night, but late in the day, Democratic leadership delayed the matter until Thursday at the earliest.
A vote by the full body will decide the political fate of the North Las Vegas Democrat, who in the past two months has been arrested twice, involuntarily hospitalized for a mental evaluation, fired from his day job and banished from the Legislature Building after public displays of bizarre behavior.
A bipartisan select committee empaneled to look into Brooks' behavior voted 6-1 Tuesday to recommend expulsion.
"I take no pleasure in making this motion," said Assemblyman Lynn Stewart, R-Henderson, who added it was for the good of the Legislature, "and I hope the good of Mr. Brooks."
The lone dissenting vote came from Assemblywoman Dina Neal, D-North Las Vegas, who favored suspension over expulsion.
Much of the evidence that committee members were privy to is confidential ? such as Brooks' medical records ? and will not be shared with all Assembly members or the public.
The secrecy presents an uncomfortable dilemma for some lawmakers as they are asked to judge the fitness of a colleague based largely on public reports and their own observations of and interactions with Brooks.
It weighed on some members of the committee before Tuesday night's meeting was closed.
Mark Ferrario, an independent counsel hired to investigate Brooks for the committee, presented the panel with two reports accompanied by roughly 900 pages of supporting documents.
Assembly Minority Leader Pat Hickey, R-Reno, and Assemblyman Wesley Duncan, R-Las Vegas, questioned why at least some of the investigative findings could not be released.
Hickey acknowledged medical privacy concerns but asked, "What is the rationale for the rest of the report that includes a lot of public documents and testimony of members that may be pertinent to our decision?"
But Ferrario said the information was so intertwined, it could not easily be split into what can or can't be made public.
He added that some of his information was only obtained under confidentiality agreements with state agencies or witnesses who were promised they would not be revealed.
"If you open the door, you open the door all the way," he said.
On Wednesday, Hickey, who voted to recommend Brooks' expulsion, said he hoped for more transparency so the public can weigh how the decision was made.
"I just think, after going through the process as a committee last night, I think that the public might better appreciate the diligence and the wrenching labor that it took to take a vote to decide to expel a person, knowing that history being behind you on this has never been done before," Hickey said.
"It's a very serious vote."
Horne on Wednesday downplayed whether keeping details of the report from all Assembly members would be a factor in the ultimate outcome. He compared it to the U.S. Congress, where members of the House and Senate intelligence committees are allowed to see top secret information, while other lawmakers are not.
"It's an enormous leap sometimes to ask your colleagues to trust you on that, but as I stated last night the members of the (select) committee were chosen for a reason, because of how their colleagues view them," Horne said.
Brooks, a 41-year-old father of four, was re-elected to a second term in November. But his public troubles began two months later, following his arrest Jan. 19 for allegedly voicing threats against Assembly Speaker Marilyn Kirkpatrick, a fellow North Las Vegas Democrat. Police said Brooks had a gun and ammunition in his car, but no charges have been filed.
He was arrested again in February after police say he threw punches and grabbed for the gun of an officer who had responded to a domestic dispute at his estranged wife's house. He faces a court hearing in May on one felony and three lesser charges.
Brooks also was hospitalized for a psychiatric evaluation after police were called to a disturbance at this grandmother's home. He posed bare-chested for a newspaper photographer and was sworn in to the Legislature when it convened Feb. 4. He was banished from the building a week later as a possible security risk.
Brooks didn't attend Tuesday's hearing.
Source: http://news.yahoo.com/historic-expulsion-vote-pending-nevada-assembly-191909257.html
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Common gene variants explain 42% of antidepressant response
Mar. 28, 2013 ? Antidepressants are commonly prescribed for the treatment of depression, but many individuals do not experience symptom relief from treatment. The National Institute of Mental Health's STAR*D study, the largest and longest study ever conducted to evaluate depression treatment, found that only approximately one-third of patients responded within their initial medication trial and approximately one-third of patients did not have an adequate clinical response after being treated with several different medications. Thus, identifying predictors of antidepressant response could help to guide the treatment of this disorder.
A new study published in Biological Psychiatry now shares progress in identifying genomic predictors of antidepressant response.
Many previous studies have searched for genetic markers that may predict antidepressant response, but have done so despite not knowing the contribution of genetic factors. Dr. Katherine Tansey of Institute of Psychiatry at King's College London and colleagues resolved to answer that question.
"Our study quantified, for the first time, how much is response to antidepressant medication influenced by an individual's genetic make-up," said Tansey.
To perform this work, the researchers estimated the magnitude of the influence of common genetic variants on antidepressant response using a sample of 2,799 antidepressant-treated subjects with major depressive disorder and genome-wide genotyping data.
They found that genetic variants explain 42% of individual differences, and therefore, significantly influence antidepressant response.
"While we know that there are no genetic markers with strong effect, this means that there are many genetic markers involved. While each specific genetic marker may have a small effect, they may add up to make a meaningful prediction," Tansey added.
"We have a very long way to go to identify genetic markers that can usefully guide the treatment of depression. There are two critical challenges to this process," said Dr. John Krystal, Editor of Biological Psychiatry. "First, we need to have genomic markers that strongly predict response or non-response to available treatments. Second, markers for non-response to available treatments also need to predict response to an alternative treatment. Both of these conditions need to be present for markers of non-response to guide personalized treatments of depression."
"Although the Tansey et al. study represents progress, it is clear that we face enormous challenges with regards to both objectives," he added. "For example, it does not yet appear that having a less favorable genomic profile is a sufficiently strong negative predictor of response to justify withholding antidepressant treatment. Similarly, there is lack of clarity as to how to optimally treat patients who might have less favorable genomic profile.."
Additional research is certainly required, but scientists hope that one day, results such as these can lead to personalized treatment for depression.
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The above story is reprinted from materials provided by Elsevier, via AlphaGalileo.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Katherine E. Tansey, Michel Guipponi, Xiaolan Hu, Enrico Domenici, Glyn Lewis, Alain Malafosse, Jens R. Wendland, Cathryn M. Lewis, Peter McGuffin, Rudolf Uher. Contribution of Common Genetic Variants to Antidepressant Response. Biological Psychiatry, 2013; 73 (7): 679 DOI: 10.1016/j.biopsych.2012.10.030
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/z5l4WA6eDzU/130328091730.htm
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